Job Description
Senior Research Scientist - Oncology Full-time Vancouver, British Columbia, Canada Apply now June 18, 2024 Job ID: 23216 AbCellera is breaking the barriers of conventional drug development to propel antibody-based medicines from target to clinic. We are a team of scientists, engineers, creatives, and business professionals who believe that advancing science enhances lives. We have developed technologies to unlock high-value drug targets, including antibody-drug conjugates and T-cell engagers for cancer, and complex transmembrane proteins for indications such as metabolic and endocrine conditions, pain, and autoimmunity.We are looking for a highly motivated Senior Research Scientist with a strong oncology and immunology background to join our team. This scientist will contribute to the assessment and development of antibody-based oncology drug candidates so that we can move programs faster and with less risk to the clinic. The position involves internal R&D as well as external collaborative research. We are looking for someone who has a passion for understanding how models can predict therapeutic action on human disease.How you might spend your days:Leading internal preclinical in vivo oncology models to support oncology programsDesigning, running, and interpreting pharmacology studies to generate in vivo proof-of-concept and build confidence in selection of molecules for clinical developmentCollaborating with in vitro biology, protein engineering, and pharmacokinetics scientists, as well as external CROs and collaborators, to execute efficient PK/PD studies to identify lead molecules and advance programs to human trialsMentoring team members in laboratory techniques related to tumour xenograft modelsReporting findings to internal program team and partners to support data-driven decisionsEvaluating available preclinical and clinical data sets to build testable biological hypotheses for oncology targets and then preclinically assessing those hypothesesDeveloping, performing, and overseeing supporting assays to assess target modulation and downstream effects at the cellular, protein, and gene levelWe’d love to hear from you if:You have 8+ years of hands-on experience in oncology, immuno-oncology, and biologics drug developmentYou have a PhD in pharmacology, immunology, or related field, plus 5-8 years of experience in a biopharmaceutical industry setting; or a MSc and 8-10 years of relevant experienceYou have proven interpersonal skills and create value on cross-functional teamsYou are genuinely curious, with an interest in discussing innovative ideas in a highly collaborative and fast paced environmentYou are good at communicating scientific and/or technical concepts with an emphasis on applicationYou are able to independently identify project needs and follow that up with constructing and implementing solutionsYou enjoy the teamwork that comes with working on complicated biological questions and building data sets that help to predict the success of therapiesWhat we offer:AbCellera’s hiring range for this role is CAD $110,000 - $137,600 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, opportunity for flexible work arrangements, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find we prioritize team building and connections across AbCellera.About AbCellera:AbCellera is a global company that discovers and develops antibody-based medicines that help people live longer, happier, and more productive lives. We are focused on bringing innovative medicines to patients, both by advancing our internal pipeline of programs and partnering with companies that have novel science or innovative technology.And it all starts with our team. We’ve built a place where people feel they are part of something bigger than themselves. A place that exists to push the limits of science and technology, and aims to bring better therapies to patients.We look for people with drive and energy. Idealists. People we love and people we trust. This may be unconventional, but it is the key to our success.To apply:Please submit your application through our website and refer toJob ID 23216in your cover letter. We apologize in advance, but we receive a large volume of applications and are only able to contact those who are selected for an interview.#LI-MS #LI-LC1